Tacrolimus相关论文
目的:回顾性分析肾移植术后稳定期受者他克莫司普通剂型转换为缓释剂型的不同转换方案的疗效和安全性，为肾移植受者他克莫司转换策......
1例38岁女性尿毒症患者行肾移植术后第5天予他克莫司1 mg口服、1次/12 h，服药第15天患者他克莫司血药谷浓度为9.8 μg/L。第17天患......
目的:探讨他克莫司(FK506)联合糖皮质激素(GC)治疗难治性肾病综合征(RNS)的疗效。方法:抽取2017年1月至2021年1月郑州市第三人民医......
The remission of renal injury in tacrolimus to sirolimus conversion renal transplant recipients is d
Background: Conversion from tacrolimus to sirolimus-based immunosuppression is associated with improved renal function a......
Safety and efficacy of tacrolimus in patients with connective tissue disease associated interstitial
Backgroud: To investigate the safety and efficacy of tacrolimus in patients with connective tissue disease associated in......
Cyclosporine A versus Tacrolimus as Immunosuppressive Therapy after Allogeneic Hematopoietic Stem Ce
Background and Objective Cyclosporine A (CsA) has been used as immunosuppressive therapy after allogeneic hematopoietic ......
The Efficacy and Safety of Tacrolimus Monotherapy in Adult-onset Nephrotic Syndrome Caused by Idiopa
Introduction: The purpose of the study is to evaluate the efficiency and safety of tacrolimus(TAC)monotherapy in the tre......
Tacrolimus(FK506)is an immunosuppressive agent which is usually applied to patients who received allotransplantation to ......
Tripterygium Wilfordii Multiglycosides Versus Tacrolimus in The Treatment of Idiopathic Membranous N
Background: Idiopathic membranous nephropathy(IMN)is a major cause of nephrotic syndrome among adults.Given the special ......
One case report of intervention in immunosuppressive agents convertion from cyclosporine to tacrolim
Aim: To explore the work pattern of clinical pharmaceutical care associated with immunosuppressive agents convertion fro......
Pharmacokinetics of once daily prolonged-release formulation of tacrolimus in pediatric nephrotic sy
Background and Objectives Tacrolimus PR is a new prolonged-release once-daily formulation of the calcineurin inhibitor t......
To investigate the efficacy and safety of tacrolimus(TAC)in treating pediatric refractory nephrotic syndrome(PRNS).First......
Population pharmacokinetics of tacrolimus in pediatric refractory nephrotic syndrome:comparison with
Different population pharmacokinetics(PPK)of tacrolimus(TAC)models have been established in various pediatric disease po......
Objective: The experience of tacrolimus(TAC)in pediatric lupus nephritis(PLN)is very limited and this study aims to inve......
Treatment of systemic-onset juvenile idiopathetic arthritis with tacrolimus based on real world stud
What is known and objectives: Limited experience of tacrolimus(TAC)treatment in systemic-onset juvenile idiopathetic art......
Inhibition of calcineurin in the prefrontal cortex induced depressive-like behavior through mTOR sig
Rational Although it has been recognized that inhibition of calcineurin induced depressive-like behavior, the underlying......
Tacrolimus Inhibit Vascular Contraction via Activation of BKca Currents by Increasing Ca2+ Sparks Re
Aim: The vasoactive properties of tacrolimus were inconsistent.There was report that tacrolimus could activate spontaneo......
AIM: To develop a therapeutic drug monitoring (TDM) network server of tacrolimus for Chinese renal transplant patients.M......
Objective: Establish and validation a HPLC for determination tacrolimus.Methods: Chromatographic column: Ultimate(R) XB-......
Effects of tacrolimus and cyclosporine treatment on metabolic syndrome and cardiovascular risk facto
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目的探讨在异基因造血干细胞移植（allo-HSCT）患者中，CYP3A5基因多态性与他克莫司血药浓度及急性移植物抗宿主病（GVHD）间的关系。方法回......
目的分析窄谱强脉冲光联合他克莫司治疗玫瑰痤疮的疗效和安全性。方法抽取2018年4月至2020年10月开封市中心医院收治的玫瑰痤疮患......
Impact of immunosuppression on incidence of post-transplant diabetes mellitus in solid organ transpl
BACKGROUND Solid organ transplantation is a life-saving intervention for end-stage organ disease.Post-transplant diabete......
目的:探讨重症肌无力(MG)患者外周血CD4n +T细胞中转录因子n Foxp1 mRNA的表达及他克莫司免疫治疗前后n Foxp1 mRN......
Comparison of Tacrolimus,Fluorometholone,and Saline in Mild-to-Moderate Contact Lens-Induced Papilla
Introduction:The purpose of this study was to compare the efficacy of tacrolimus,fluorometholone,and saline in the t......
AIM:To determine the efficacy and safety of rapid induction therapy with oral tacrolimus without a meal in steroid-refra......
目的:他克莫司是一种新型钙调磷酸酶抑制剂,目前被广泛应用于成人肝或肾移植术后,也被逐渐广泛应用于肾病综合征患儿。他克莫司缓......
Midterm outcomes of prospective,randomized,single-center study of the Janus tacrolimus-eluting stent
Background Long-term efficacy and safety of tacrolimus-eluting stent(Janus)for treatment of coronary artery diseasein p......
Tacolimus Postconditioning Alleviates Apoptotic Cell Death in Rats after Spinal Cord Ischemia-reperf
The effects of tacrolimus postconditioning on protein-serine-threonine kinases(Akt) phosphorylation and apoptotic cell d......
·Rural opioid use disorder treatment depends on family physicians农村阿片类药物联用的控制依赖家庭医生·Stretching for p......
AIM: To investigate the impact of minimum tacrolimus(TAC) on new-onset diabetes mellitus(NODM) after liver transplantati......
对先天性胆道闭锁患者施行肝移植术后肝动脉血栓形成（HAT）是一种严重并发症，发生率为21％～40％，多数需要再次肝移植。作者回顾性分析了美国......
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Both brain injury and tacrolimus have been reported to promote the regeneration of injured peripheral nerves. In this st......
目的探讨他克莫司联合小剂量激素治疗IgA肾病的临床疗效。方法将收治的IgA肾病84例按照数字表法随机分为研究组和对照组，对照组给予......
目的观察他克莫司软膏联合奥硝唑、克拉霉素治疗酒渣鼻合并面部激素依赖性皮炎的疗效及安全性。方法选取酒渣鼻合并面部激素依赖性......
目的：：为临床药师参与特发性膜性肾病的治疗提供参考。方法：对临床药师参与的3例特发性膜性肾病的用药情况进行分析。结果：采用糖皮质......
目的 探讨他克莫司对阿霉素肾病大鼠肾组织中多药耐药基因1(MDR1)表达的影响.方法 通过单侧肾摘除联合尾静脉重复注射阿霉素的方法......
目的比较高效液相色谱串联质谱(HPLC-MS/MS)法与化学发光微粒子免疫分析法(CMIA)测定他克莫司(FK506)浓度结果的相关性,以及2种方......
目的 探讨小剂量他克莫司添加治疗难治性全身型重症肌无力(MG)的疗效及可能机制.方法 纳入临床确诊的18例难治性全身型MG患者(Osse......
Efficacy of mycofenolate mofetil for steroid-resistant acute rejection after living donor liver tran
AIM: To discuss the use of mycophenolate mofetil (MMF) as an immunosuppressant in steroid resistant rejection after live......
1例52岁女性患者因重症再生障碍性贫血行异基因造血干细胞移植术,术后服用环孢素预防移植物抗宿主病。2个月后因肾功能不全,换用他......
1例72岁男性患者因不典型膜性肾病口服他克莫司(2 mg,2次/d)及甲泼尼龙(8 mg,1次/d)。约6个月后,患者出现纳差、口干、乏力。实验......
目的评价婴幼儿肝移植术后应用含他克莫司免疫抑制方案的有效性与安全性。方法收集2013年6月至2014年9月因胆道闭锁在北京友谊医院......
Cyclosporine versus tacrolimus in patients with HCV infection after liver transplantation: Effects o
AIM: To determine the effects of the calcineurin inhibitors, cyclosporine and tacrolimus, on hepatitis C virus (HCV) rep......
1例有白塞病病史的41岁男性急性髓系白血病患者异基因造血干细胞移植期间静脉泵入他克莫司(2.5～3.0 mg/24 h)，维持血药浓度在10.0～15.......
1例31岁男性患者行异体肾移植术后接受三联抗排异治疗(他克莫司3 mg、1次/12 h，麦考酚钠肠溶片720 mg、2次/d，醋酸泼尼松龙片80 mg、......
目的探讨重症肌无力（MG）患者小剂量他克莫司治疗2年复发率及其影响因素。方法回顾性分析2011年2月至2016年2月接受他克莫司治疗的110......
